2018 - Current F-150 Ambient Lighting
Below is the SSM from Ford regarding the ambient lighting changes to the 2018+ F Series pickup trucks. There is not a simple programming change to fix this. All of the LED lighting assemblies in the vehicle have a single color LED (ice blue).
2018+ - F-150 - Ambient Lighting - Multi-Color Settings Inoperative ***SSM 46841***
2018+ F-150 vehicles equipped with ambient lighting will only have a single color. The multi-color option, ability to dim and turn on/off are no longer available in 2018 model year. No repair attempts should be made to address the ability to enable color change, dim or turn on/off the ambient lighting feature
https://www.4dtech.com/products/ford/f-150/2018/